Unlike traditional NMR textbooks for chemists, this fresh look at the topic combines theory, technology and application in a wide range of fields, targeting biochemists, medicinal chemists, and structural biologists, as well as organic chemists. The text has been developed from a one-semester graduate-level course taught by the authors at the University of Zurich, and offers numerous intuitive illustrations, training exercises and plain-language explanations of complex theory. Divided into four major parts, the first introduces the basics of NMR, followed by a discussion of the underlying theory in part two. Part three deals with NMR instrumentation and practical aspects of experiment setup and execution, while the fourth part focuses on the main application of NMR in the biomolecular sciences, structure determination of biomolecules from steroids to proteins to nucleic acids. With its focus on practical aspects and applications, this text will prove useful long after leaving college, by helping users to select experimental methods and in setting up and running their own NMR experiments.

Hersteller:
Wiley-VCH GmbH
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Boschstr. 12
DE 69469 Weinheim

Oliver Zerbe is the head of the NMR department at the University of Zurich. He studied chemistry and obtained his PhD under the supervision of Wolfgang von Philipsborn in Zurich. After a Postdoctoral stay in the group of Kurt Wüthrich at the ETH Zurich he conducted his Habilitation with Gerd Folkers at the Institute of Pharmaceutical Sciences at the ETH. In 2003 he returned to his present location at the University of Zurich, where is now is a professor in the Department of Chemistry. His main interests are structures of proteins, particularly of membrane proteins. Oliver Zerbe is the author of approx. 100 scientific publications in peer-reviewed journals and has edited one book, 'NMR in drug research'.

Leseprobe