InhaltsangabeI. Human Sperm Chromatin: Structure and Function1. Sperm Chromatin: An Overview Rodney Balhorn2. Spermatogenesis: An Overview  Rakesh Sharma and Ashok Agarwal3. Sperm Nucleoproteins Rafael Oliva and Judit Castillo4. The Relationship Between Chromatin Structure and DNA Damage in Mammalian Spermatozoa Kenneth Dominguez, Chris D. R. Arca, and W. Steven Ward5. Chromosome Positioning in Spermatozoa Andrei Zalensky, Olga Mudrak, and Irina Zalenskaya 6. Sperm Mitochondrial DNA Justin C. St. John and Bianca St. John7. The Sperm Epigenome Donovan Chan and Jacquetta Trasler 8. RNA Expression in Germ Cells During Spermatogenesis (Germ Cell Transcriptome)  TinLap Lee, Albert HoiHung Cheung, Owen M. Rennert, and WaiYee ChanII. Laboratory Evaluation of Sperm Chromatin9. Sperm Chromatin Structure Assay (SCSA®): 30 Years' Experience with the SCSA® Donald P. Evenson 10. Sperm Chromatin Dispersion Test: Technical Aspects and Clinical Applications Jaime Gosálvez, Carmen López-Fernández, and José Luís Fernández 11. Basic and Clinical Aspects of the Sperm Chromomycin A3 Assay Giancarlo Manicardi, Davide Bizzaro, and Denny Sakkas12. Cytochemical Tests for Sperm Chromatin Maturity Igor Tsarev and Juris Erenpreiss 13. Acridine Orange Test for Assessment of Human Sperm DNA Integrity Alex C. Varghese, C. Fischer-Hammadeh, and M. E. Hammadeh 14. Laboratory Evaluation of Sperm Chromatin: TUNEL Assay Rakesh Sharma and Ashok Agarwal15. The Basic and Clinical Aspects of the Sperm Comet Assay Luke Simon and Sheena E. M. Lewis16. Assays Used in the Study of Sperm Nuclear Proteins Timothy G. Jenkins, Benjamin R. Emery, and Douglas T. Carrell17. Sperm Epigenetic Profile Cristina Joana Marques, Alberto Barros, and Mário Sousa18. Clinical Significance of Sperm RNA JeanPierre Dadoune, Isabelle GaleraudDenis, and Serge Carreau III. Biological and Clinical Determinants of Sperm Chromatin Damage19. Role of Oxidative Stress in the Etiology of Sperm DNA Damage R. John Aitken and Geoffry N. De Iuliis20. Abortive Apoptosis and Sperm Chromatin Damage Hasan M. ElFakahany and Denny Sakkas21. Spermiogenesis in Sperm Genetic Integrity MarieChantal Grégoire, Frédéric Leduc, and Guylain Boissonneault22. Male Subfertility and Sperm Chromatin Damage Mona Bungum, Aleksander Giwercman, and Marcello Spanò 23. Aging and Sperm DNA Damage Fábio F. Pasqualotto and Eleonora B. Pasqualotto24. Cancer in Males: Implications for Sperm Quality, Fertility, and Progeny Outcome Peter Chan and Bernard Robaire25. Sperm Chromatin and Environmental Factors Aleksander Giwercman26. Effects of Male Accessory Gland Infection on Sperm Parameters Aldo E. Calogero, Sandro La Vignera, Rosita A. Condorelli, Rosario D'Agata, and Enzo VicariIV. Sperm Chromatin and Assisted Reproductive Technology Outcomes27. The Impact of Sperm Processing and Cryopreservation on Sperm DNA Integrity Dan Yu, Luke Simon, and Sheena E. M. Lewis28. Structure of Chromatin in Human Sperm Bound to Hyaluronic Acid: The Benefits of PICSI Dish Mediated Sperm Selection Leyla Sati and Gabor Huszar29. Electrophoretic Sperm Separation Steven Fleming and R. John Aitken30. Antioxidants and Sperm DNA Damage Armand Zini and Maria San Gabriel31. Sperm Chromatin and ART (IUI, IVF, and ICSI) Pregnancy Mona Bungum32. Sperm DNA Damage and Pregnancy Loss After IVF/ICSI Armand Zini and Jason Matthew Boman33. Postnatal Effects of Sperm Chromatin Damage Miriam PérezCrespo, Raúl FernándezGonzález, Miguel Ángel Ramírez, Eva Pericuesta, Alexandra Calle, and Alfonso GutiérrezAdán34. Evaluation of Chromatin and DNA Integrity in Testicular Sperm Armand Zini and Naif Al-HathalV. Protocols and Integrity Tests35. The Alkaline Comet Assay Sheen