This volume provides a comprehensive, up-to-date overview on pediatric and adolescent gynecological endocrinology. It covers a very wide range of topics with a particular focus on disorders of sex differentiation, pubertal maturation, growth disorders, primary and secondary amenorrhea, menstrual disorders in adolescents and young adults, sexuality, contraception, and pregnancy. The authors are international well-known experts who document the latest clinical experience in this continuously evolving field and provide practical guidance on the evaluation and treatment of female pubertal problems.

The book is published within the International Society of Gynecological Endocrinology (ISGE) Series and is based on the 2015 International School of Gynecological and Reproductive Endocrinology (ISGRE) Summer Course. It will be an invaluable reference for gynecologists, endocrinologists, pediatricians, and experts in womens health.

Andrea R. Genazzani is President of the International Society of Gynecological Endocrinology (ISGE), President of the European Society of Gynecology (ESG), General Secretary of the International Academy of Human Reproduction (IAHR), Fellow ad eundem of the Royal College of Obstetricians and Gynaecologists, Editor-in-Chief of Gynecological Endocrinology since 1987. He is author of more than 827 papers in peer reviewed journals and Editor of more than 42 books. 
Charles Sultan is Professor of Pediatric Endocrinology. He is Chief of the INSERM group, Chief of the Hormone Center, and Chief of the Unit of Pediatric Endocrinology at the University Hospital in Montpellier. Professor Sultan is Professor and deputy-dean of the Faculty of Medicine at the University of Montpellier. He is author of more than 435 papers.

PART 1 Brain Dimorphism.- Dimorphism of human brain: the basis of the gender differences.- PART 2 Disorders of sex Differentiation.- Management of children/adolescents with disorders of sex differentiation (DSD).- Surgery of feminization in DSD patients.- PART 3 Puberty.- Onset of puberty: genetic, endocrine and environmental factors.- CPP (Central Precocious Puberty): from diagnosis to treatment to get a normal development.- Peripheral precocious puberty: more and more frequent.- Adrenarche and hyper-androgenism.- The hypothalamo-pituitary ovarian axis during pubertal maturation.- PART 4 Primary and Secondary Amenorrhea.- Primary amenorrhea due to gonadal dysgenesis and primary ovarian failure: diagnosis, management and follow up.- Functional hypothalamic amenorrhea as stress induced defensive system.- Anorexia nervosa in adolescence: psycho-social, clinical and therapeutic aspects.- Long term cardiovascular risks associated with amenorrhea.- PART 5 Growth Disorders.- Female growth disorders: differential diagnosis and management.- Impaired bone development during adolescence: diagnosis, treatment and follow-up.- PART 6 hyperandrogenism.- Management of mild and moderate hyperandrogenism in the adolescent.- PART 7 Pre-menstrual Disorders.- Pre-menstrual disorders and headache in adolescent and young adults.- PART 8 elayed Puberty.- Delayed puberty: impact on fertility.- PART 9 Premature Ovarian Failure.- Premature ovarian failure in adolescence and young adults: From diagnosis to therapy and follow-up for fertility preservation.- PART 10 sexuality, contraception, and pregnancy.- Discovering sexualIty in adolescence.- The choice of the better contraception for the adolescents.- Emergency contraception and abortion.- Pregnancy in adolescents and young adults