In 1940s and '50s America, polio is as dreaded as the atomic bomb. No one's life is untouched by this disease that kills or paralyzes its victims, particularly children. Outbreaks of the virus across the country regularly put American cities in lockdown. Some of the world's best minds are engaged in the race to find a vaccine. But Dorothy Horstmann is not focused on beating her colleagues to the vaccine. She just wants the world to have a cure. Based on the true story of the woman who stopped a pandemic.