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Biopharmaceutics Applications in Drug Development

Erschienen am 26.11.2007, 1. Auflage 2008
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Bibliografische Daten
ISBN/EAN: 9780387723785
Sprache: Englisch
Umfang: xxii, 396 S.
Einband: gebundenes Buch

Beschreibung

Inhaltsangabeto Biopharmaceutics and its Role in Drug Development.- Molecular and Physicochemical Properties Impacting OralAbsorptionofDrugs.- Dissolution Testing.- Drug Absorption Principles.- Evaluation of Permeability and P-glycoprotein Interactions: Industry Outlook.- Excipients as Absorption Enhancers.- IntestinalTransporters in Drug Absorption.- Bioavailability and Bioequivalence.- A Biopharmaceutical Classification System Approach to Dissolution: Mechanisms and Strategies.- Food Effects on Drug Bioavailability: Implications for New and Generic Drug Development.- In Vitro-In Vivo Correlation on Parenteral Dosage Forms.- In Vitro-In Vivo Correlation in Dosage Form Development: Case Studies.

Produktsicherheitsverordnung

Hersteller:
Springer Verlag GmbH
juergen.hartmann@springer.com
Tiergartenstr. 17
DE 69121 Heidelberg

Inhalt

Introduction To Biopharmaceutics And Its Role In Drug Development.- Molecular and Physicochemical Properties Impacting Oral Absorption of Drugs.- Dissolution Testing.- Drug Absorption Principles.- Current Industrial Practices of Evaluating Permeability/Absorption and P-glycoprotein Interaction.- Excipients As Absorption Enhancers.- Intestinal Transporters In Drug Absorption.- Bioavailability And Bioequivalence.- A Biopharmaceutical Classification System Approach to Dissolution: Mechanisms and Strategies.- Food Effects On Drug Bioavailability: Implications For New And Generic Drug Development.- In Vitro-In Vivo Correlation on Parenteral Dosage Forms.- In Vitro-In Vivo Correlation in Dosage Form Development: Case Studies.- Index.